Naltrexone Intramuscular Route Side Effects

The first published study on the initial efficacy, safety, and tolerability of Vivitrex® for treating alcohol dependence was a double-blind, placebo-controlled, randomized, multi-site, 16 week clinical trial (Johnson et al 2004). Twenty-five alcohol-dependent individuals were assigned to receive intramuscular injections of Vivitrex® (400 mg) every 4 weeks, while five participants received placebo via the same route of administration every 4 weeks. Vivitrex® appeared to be relatively safe and well tolerated; the most common adverse events were non-specific abdominal pain, nausea, pain at the injection site, and headaches. Two Vivitrex® recipients and zero placebo recipients discontinued treatment because of side effects. One participant dropped out due to induration at the injection site, and one was discontinued by the research staff because of an allergic reaction that resulted in angioedema, which resolved soon after the participant stopped taking the medication. In the exercise of scientific caution, no inferential statistical testing was conducted on these descriptive values.

“Patients should be warned of the risk of hepatic injury and advised to seek medical attention if they experience symptoms of acute hepatitis,” the companies said. This summary was prepared by the John M. Eisenberg Center for Clinical Decisions and Communications Science at Baylor College of Medicine, Houston, TX. It was written by Amelia Williamson Smith, M.S., https://www.editions-rlo.com/excellentcocktail-party-catering-in-hong-kong/ Thomas Kosten, M.D., and Michael Fordis, M.D. People with alcohol use disorder reviewed this summary. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Before having any laboratory test, tell your doctor and the laboratory personnel that you are receiving naltrexone injection.

Severe Injection Site Reactions

It remains a significant health challenge; according to the National Institute on Alcohol Abuse and Alcoholism, 29.5 million people in the US had AUD in 2021, including 894,000 young people aged 12-17. Get professional help from an online addiction and mental health counselor from BetterHelp. While all drugs can be dangerous, especially illegal drugs or drugs that are used without a prescription, some are more dangerous than others. Drug-related deaths are on the rise across the United States, and every year tens of thousands of Americans die from drug-related causes. Some drugs can be deadly after a single dose, while others cause death only after extended use. The following list includes some of the most commonly abused substances and chemicals confirmed by the CDC and DEA.

Vivitrol effectively blocks opioid and alcohol neurological effects, binding to receptor sites in place of drugs. When you use alcohol and narcotics, parts of your brain make you feel pleasure and intoxication. When these areas are blocked, you feel less need to drink alcohol. You don’t feel the “high” pleasure sensation that makes you want to drink. Disulfiram (brand name Antabuse) is another medicine that is sometimes used to treat alcoholism.

Vivitrol for alcohol dependence

In comparison, only 2% of people who took a placebo had an increase in AST. In a 24-week clinical trial for the treatment of opioid dependence, no one reported a depressed mood or suicidal thinking. Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

It is responsible for costing the United States billions of dollars yearly and over 480,000 deaths in recent years. Despite these findings, smoking cigarettes “is the leading preventable cause of death.” Tobacco destroys the body’s vital organs, most commonly the lungs and https://sernur.club/catalog/kozmetika/nochnoy-krem-dlya-litsa.html throat. It is highly addictive and sought out for its ability to produce relaxation. Another dangerous component of tobacco is its ability to cause secondhand smoke. Individuals who do not smoke but live with a smoker risk lung-related illness and death through smoke.

What are the side effects of Vivitrol?

The method of analysis estimates the average event rate
ratio over time taking into account patient discontinuation. Treatment providers should not avoid delivering regular, adequate psychosocial support to alcohol-dependent https://www.gamez.ru/sol/365_full.htm individuals just because monthly depot injections are convenient. Before being introduced, the long-acting formulations would have been assessed against a background of psychosocial support.